Jan Baumbach

Latest

• DIGGER 2.0: digging into the functional impact of differential splicing on human and mouse disorders
• Paper 'On the limits of 16S rRNA gene-based metagenome prediction and functional profiling' now available
• Alternative splicing in mechanically stretched podocytes as a model of glomerular hypertension
• Inference of differential gene regulatory networks using boosted differential trees
• Network medicine-based epistasis detection in complex diseases: ready for quantum computing
• On the limits of 16S rRNA gene-based metagenome prediction and functional profiling
• RNA sequencing depth guidelines for the study of alternative splicing
• Alternative splicing analysis benchmark with DICAST
• Alternative splicing impacts microRNA regulation within coding regions
• Lacking mechanistic disease definitions and corresponding association data hamper progress in network medicine and beyond
• Mo1903 Processed polymeric diets exacerbate tumorigenesis in murine models of ATF6-driven colon cancer
• Network-based approaches for modeling disease regulation and progression
• New Enhancing MRI Lesions Associate with IL-17, Neutrophil Degranulation and Integrin Microparticles: Multi-Omics Combined with Frequent MRI in Multiple Sclerosis
• The FeatureCloud Platform for Federated Learning in Biomedicine: Unified Approach
• Hypothesis of a potential BrainBiota and its relation to CNS autoimmune inflammation
• Medical data safety via federated machine learning
• NeDRex—an integrative and interactive network medicine platform for drug repurposing
• Not Quite the Same: How Alternative Splicing Affects Protein Interactions
• P057 Mucosal microbiota adapts to ATF6-induced alterations in host lipid metabolism with prognostic value in colorectal cancer
• Privacy-Preserving Artificial Intelligence Techniques in Biomedicine
• Robust disease module mining via enumeration of diverse prize-collecting Steiner trees
• sPLINK: a hybrid federated tool as a robust alternative to meta-analysis in genome-wide association studies
• Systematic analysis of alternative splicing in time course data using Spycone
• The Limits of Molecular Signatures for Pancreatic Ductal Adenocarcinoma Subtyping
• Tumour cell budding and spread through air spaces in squamous cell carcinoma of the lung—Determination and validation of optimal prognostic cut-offs
• A framework for modeling epistatic interaction
• ASimulatoR: splice-aware RNA-Seq data simulation
• BiCoN: network-constrained biclustering of patients and omics data
• CSF proteome in multiple sclerosis subtypes related to brain lesion transcriptomes
• DIGGER: exploring the functional role of alternative splicing in protein interactions
• Enabling single-cell trajectory network enrichment
• Functional enrichment of alternative splicing events with NEASE reveals insights into tissue identity and diseases
• Lessons from the COVID-19 pandemic for advancing computational drug repurposing strategies
• Long-term instability of the intestinal microbiome is associated with metabolic liver disease, low microbiota diversity, diabetes mellitus and impaired exocrine pancreatic function
• Network analysis methods for studying microbial communities: A mini review
• Network medicine for disease module identification and drug repurposing with the NeDRex platform
• The AIMe registry for artificial intelligence in biomedical research
• The FeatureCloud AI Store for Federated Learning in Biomedicine and Beyond
• Comparative single-cell trajectory network enrichment identifies pseudo-temporal systems biology patterns in hematopoiesis and CD8 T-cell development
• EpiGEN: an epistasis simulation pipeline
• Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing
• Importance of considering the growth response after partial harvesting and economic risk of discounted net revenues when optimizing uneven-aged forest management
• Multiple Sclerosis Atlas: A Molecular Map of Brain Lesion Stages in Progressive Multiple Sclerosis
• NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype