New Recommendations for Optimal Sequencing Depth in Alternative Splicing Studies

News |

As part of an international research team led by Olga Tsoy from the University of Hamburg, the Division of Data Science in Biomedicine contributed to the development of new guidelines for determining the optimal sequencing depth in RNA sequencing (RNA-Seq) studies focusing on alternative splicing (AS). By analyzing extensive RNA-Seq datasets from human tissues such […]

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Epistasis Disease Atlas

Software & Resources |

The EDA is a comprehensive database focused on epistatic interactions, analyzing how groups of genes work together to cause complex diseases. The atlas currently covers Alzheimer’s, rheumatoid arthritis, bipolar disorder, coronary heart disease, inflammatory bowel disease, type 1 and type 2 diabetes, and hypertension. Data is accessible through a user-friendly R-Shiny app for searching, visualization,

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Sys_CARE

Sys_CARE

Projects |

Sys_CARE – Systems Medicine Investigation of Alternative Splicing in Cardiac and Renal Diseases – is a collaborative research project between the Technical University of Munich, Greifswald University, and the Saarland University. The overall goal of the project is to elucidate the role of alternative splicing in cardiac and renal diseases using systems medicine approaches and

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